Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells

Nanomaterials have published an article by Bissardon et Al in which scientists have investigated “the impact of sub-toxic concentrations of Se0 functionalized nanoparticles (SeNPs) on prostate cancer PC-3 cells and determined their intracellular localization and fate”.  Selenium 0 (Se0) is a powerful anti-proliferative agent in cancer research. Their abstract concludes: “our findings provide new insight to further study the various mechanisms of cytotoxicity of SeNPs.”

PC-3 cells were plated onto Silson’s silicon nitride membranes of size 1.5 mm × 1.5 mm and 500 nm thicknes, and then analyzed at the hard X-ray Nanoprobe beamline, I14, at Diamond Light Source.

Follow this link to read the entire paper!

Case studies

Competing anisotropies in the chiral cubic magnet Co8Zn8Mn4 unveiled by resonant x-ray magnetic scattering

Competing anisotropies in the chiral cubic magnet Co8Zn8Mn4 unveiled by resonant x-ray magnetic scattering

arXiv has published an article by Ukleev et Al about the use of x-ray resonant magnetic small-angle scattering to in...

Vortex motion in reconfigurable three-dimensional superconducting nanoarchitectures

Vortex motion in reconfigurable three-dimensional superconducting nanoarchitectures

arXiv has published an article by Zhakina et Al on their research involving the harnessing of 3D nanopatterning in o...

On the reproducibility of electron-beam lithographic fabrication of photonic nanostructures

On the reproducibility of electron-beam lithographic fabrication of photonic nanostructures

Nature Scientific Reports has published an article by Sahoo et Al on the usage of photonic nanostructures for novel ...

Nanoscintillator Coating: A Key Parameter That Strongly Impacts Internalization, Biocompatibility, and Therapeutic Efficacy in Pancreatic Cancer Models

Nanoscintillator Coating: A Key Parameter That Strongly Impacts Internalization, Biocompatibility, and Therapeutic Efficacy in Pancreatic Cancer Models

Small Science published by Wiley-VCH GmbH has released an article by Fulbert et Al about the study of nanoscintillat...

Native cryo-correlative light and synchrotron X-ray fluorescence imaging of proteins and essential metals in developing neurons

Native cryo-correlative light and synchrotron X-ray fluorescence imaging of proteins and essential metals in developing neurons

ChemRxiv has published an article by Ortega et Al about the study of cellular functions of essential metals. The abs...

Observing High-Cycle Fatigue Damage in Freestanding Gold Thin Films with Bulge Testing and Intermittent TEM Imaging

Observing High-Cycle Fatigue Damage in Freestanding Gold Thin Films with Bulge Testing and Intermittent TEM Imaging

Advanced Engineering Materials has published an article by Krapf et Al about their research of a "new experimental w...

Highly confined incident-angle-robust surface phonon polariton bound states in the continuum metasurfaces

Highly confined incident-angle-robust surface phonon polariton bound states in the continuum metasurfaces

arXiv has published a paper by Nan et Al about research of photonic technologies. The experimental results introduce...

In Situ X-ray Absorption Spectroscopy of LaFeO3 and LaFeO3/LaNiO3 Thin Films in the Electrocatalytic Oxygen Evolution Reaction

In Situ X-ray Absorption Spectroscopy of LaFeO3 and LaFeO3/LaNiO3 Thin Films in the Electrocatalytic Oxygen Evolution Reaction

The Journal of Physical Chemistry C has published an article by Che et Al about their study of the "electrocatalytic...

Characterization of MIRCOM, IRSN’s new ion microbeam dedicated to targeted irradiation of living biological samples

Characterization of MIRCOM, IRSN’s new ion microbeam dedicated to targeted irradiation of living biological samples

HAL Open Science has published a paper by Vianna-Legros et Al, about the "development and commissioning of the IRSN'...